Wenjie Song Selected Research

vestronidase alfa

9/2019	Individual heat map assessments demonstrate vestronidase alfa treatment response in a highly heterogeneous mucopolysaccharidosis VII study population.
5/2019	Correction to: Pharmacokinetic and Pharmacodynamic Modeling to Optimize the Dose of Vestronidase Alfa, an Enzyme Replacement Therapy for Treatment of Patients with Mucopolysaccharidosis Type VII: Results from Three Trials.
1/2019	Pharmacokinetic and Pharmacodynamic Modeling to Optimize the Dose of Vestronidase Alfa, an Enzyme Replacement Therapy for Treatment of Patients with Mucopolysaccharidosis Type VII: Results from Three Trials.
1/2018	A novel Blind Start study design to investigate vestronidase alfa for mucopolysaccharidosis VII, an ultra-rare genetic disease.

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Wenjie Song Research Topics

Disease

13	Neoplasms (Cancer) 04/2024 - 07/2009
12	Hepatocellular Carcinoma (Hepatoma) 01/2023 - 02/2010
4	Neoplasm Metastasis (Metastasis) 09/2023 - 09/2013
4	Mucopolysaccharidosis VII (Sly Syndrome) 09/2019 - 01/2018
3	Femoral Neck Fractures 08/2023 - 06/2022
3	Tertiary Lymphoid Structures 01/2023 - 01/2021
3	Liver Neoplasms (Liver Cancer) 01/2023 - 12/2017
3	Breast Neoplasms (Breast Cancer) 01/2019 - 07/2009
2	Sclerosis 08/2023 - 10/2022
2	Diarrhea 01/2022 - 01/2020
2	Carcinoma (Carcinomatosis) 01/2022 - 07/2009
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2019 - 03/2016
2	Glioma (Gliomas) 05/2017 - 12/2016
2	Body Weight (Weight, Body) 04/2017 - 10/2015
1	Cholangiocarcinoma 04/2024
1	Myocardial Infarction 12/2023
1	Arteriosclerosis Obliterans 12/2023
1	Coronary Disease (Coronary Heart Disease) 12/2023
1	Lung Neoplasms (Lung Cancer) 09/2023
1	Pneumonia (Pneumonitis) 09/2023
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 09/2023
1	Adenocarcinoma of Lung 09/2023
1	Deafness (Deaf Mutism) 08/2023
1	Femoral Fractures (Femoral Fracture) 08/2023
1	Hemorrhagic Shock 01/2023
1	Hemorrhage 10/2022
1	Abdominal Pain (Pain, Abdominal) 01/2022
1	Fever (Fevers) 01/2022
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2022
1	Esophageal Squamous Cell Carcinoma 01/2022
1	Thrombosis (Thrombus) 01/2022
1	Stroke (Strokes) 01/2021
1	Wounds and Injuries (Trauma) 01/2021
1	Reperfusion Injury 01/2021
1	Brain Ischemia (Cerebral Ischemia) 01/2021
1	Glioblastoma (Glioblastoma Multiforme) 01/2020
1	Autoimmune Diseases (Autoimmune Disease) 10/2019
1	Mucopolysaccharidoses 09/2019

Drug/Important Bio-Agent (IBA)

5	Biomarkers (Surrogate Marker)IBA 04/2024 - 03/2016
4	Long Noncoding RNAIBA 01/2023 - 03/2016
4	vestronidase alfaIBA 09/2019 - 01/2018
3	Matrix Metalloproteinases (MMPs)IBA 12/2023 - 09/2013
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2022 - 09/2013
3	Sorafenib (BAY 43-9006)FDA Link 12/2022 - 12/2017
3	EnzymesIBA 09/2019 - 03/2010
3	Small Interfering RNA (siRNA)IBA 01/2019 - 12/2016
3	Circular RNAIBA 01/2019 - 09/2015
2	InterleukinsIBA 12/2023 - 04/2017
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2023 - 04/2017
2	MicroRNAs (MicroRNA)IBA 09/2023 - 01/2016
2	ElementsIBA 08/2023 - 10/2022
2	ChemokinesIBA 10/2022 - 01/2022
2	CytokinesIBA 10/2022 - 01/2022
2	Therapeutic UsesIBA 01/2021 - 09/2010
2	GlucuronidaseIBA 09/2019 - 01/2019
2	Paclitaxel (Taxol)FDA LinkGeneric 02/2010 - 07/2009
1	NucleolinIBA 04/2024
1	Protein SIBA 04/2024
1	C-Reactive ProteinIBA 12/2023
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 09/2023
1	Antisense RNA (Anti-Sense RNA)IBA 09/2023
1	Small Nucleolar RNA (snoRNA)IBA 09/2023
1	XIST non-coding RNAIBA 09/2023
1	TitaniumIBA 08/2023
1	6-bromo-2-naphthyl sulfate (BNS)IBA 08/2023
1	AlloysIBA 08/2023
1	CopperIBA 01/2023
1	Histone Deacetylase InhibitorsIBA 01/2023
1	BilirubinIBA 12/2022
1	MetalsIBA 10/2022
1	nimotuzumabIBA 01/2022
1	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 01/2022
1	Eosine Yellowish-(YS) (Eosin)IBA 01/2022
1	Hematoxylin (Haematoxylon)IBA 01/2022
1	Competitive Endogenous RNAIBA 01/2021
1	Evans Blue (Blue, Evans)FDA Link 01/2021
1	3,5-dicaffeoylquinic acidIBA 01/2021
1	Immune Checkpoint InhibitorsIBA 01/2021
1	scutellarinIBA 01/2021
1	Irinotecan (Camptosar)FDA LinkGeneric 01/2020
1	Antinuclear AntibodiesIBA 10/2019
1	capmatinibIBA 01/2019
1	Multidrug Resistance-Associated Protein 2IBA 01/2019
1	Tyrosine Kinase InhibitorsIBA 01/2019
1	ATP-Binding Cassette Sub-Family B Member 4IBA 01/2019
1	GlycosaminoglycansIBA 01/2019
1	Proteins (Proteins, Gene)FDA Link 01/2019
1	Estrogens (Estrogen)FDA Link 11/2018
1	Nerve Growth Factors (Neurotrophins)IBA 11/2018

Therapy/Procedure

7	Immunotherapy 01/2023 - 01/2016
4	Therapeutics 01/2020 - 02/2010
2	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2021 - 04/2017
2	Enzyme Replacement Therapy 05/2019 - 01/2019
1	Cochlear Implantation 08/2023
1	Internal Fixators 08/2023
1	Stents 10/2022
1	Surgical Portasystemic Shunt (Portosystemic Shunt) 10/2022
1	Arthroplasty 06/2022
1	Chemoradiotherapy 01/2022
1	Radiotherapy 01/2022